tlr1 inhibitor cu cpt 22 (Tocris)
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tlr1 inhibitor cu cpt 22
Tlr1 Inhibitor Cu Cpt 22, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 32 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tlr1+inhibitor+cu+cpt+22/CU+CPT+22/pmc11734630-60-4-10
Average 94 stars, based on 32 article reviews
Tlr1 Inhibitor Cu Cpt 22, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 32 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/tlr1+inhibitor+cu+cpt+22/CU+CPT+22/pmc11734630-60-4-10
Average 94 stars, based on 32 article reviews
tlr1 inhibitor cu cpt 22 - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti– Helicobacter pylori IgG Titers"
Article Title: Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti– Helicobacter pylori IgG Titers
Journal: Gastroenterology
doi: 10.1053/j.gastro.2022.01.011
Figure Legend Snippet: Summary of Single-Nucleotide Polymorphism (SNP) at the TLR1/6/10 Locus in Discovery, Replication, and Combined Meta-analysis
Techniques Used:
Figure Legend Snippet: Measurement of Toll-like receptor 1 (TLR1)–positive cells by flow cytometry. Dot plots illustrating the percentage of TLR1 positive cells in healthy subjects genotyped for rs28393318. The mean ± SEM and statistical significance among 3 genotypes are shown. ( A ) TLR1 positivity of monocytes in AA (n = 12), GA (n = 9), and GG (n = 5) carriers. ( B ) TLR1 positivity of polymorphonuclear neutrophils in AA (n = 9), GA (n = 6), and GG (n = 5) carriers.
Techniques Used: Flow Cytometry
Figure Legend Snippet: Cytokine production by peripheral blood mononuclear cells (PBMCs) on stimulation with Helicobacter pylori . ( A ) Interleukin-8 (IL8), ( B ) interleukin-10 (IL10), and ( C ) tumor necrosis factor α (TNFα) levels in PBMCs of healthy subjects (n = 22). Cytokine levels were measured at baseline without stimulation and after H pylori exposure in the absence and presence of TLR1 inhibitor CU-CPT-22.
Techniques Used:
Figure Legend Snippet: Time course of cytokine production by peripheral blood mononuclear cells (PBMCs) on stimulation with Toll-like receptor 1 (TLR1) ligand Pam3Cys4 or Helicobacter pylori in AA and GG carriers of rs28393318. ( A, D ) Interleukin-8 (IL8), ( B, E ) IL10, and ( C, F ) tumor necrosis factor α (TNFα) levels measured at different time points after stimulation with ( A – C ) TLR1 agonist Pam3Cys4 or ( D – F ) H pylori (HP). The results are stratified for AA (n = 12) and GG (n = 8) carriers of rs28393318. The mean ± SEM and statistical significance between genotypes are shown. CFU, colony-forming unit.
Techniques Used:
Related Articles
Enzyme-linked Immunosorbent Assay:Article Title: Toll-Like Receptor 1 Locus Re-examined in a Genome-Wide Association Study Update on Anti-Helicobacter pylori IgG Titers. Article Snippet: After 24 hours of incubation, wells were washed and PBMCs stimulated with 1 million colony-forming units of heat-killed H pylori (strain ATCC-43504 [cagAþ, vacA(s1/m1), iceAþ, babA2þ]; Manassas, VA) grown on Trypticase Soy Agar (Oxoid, Hampshire, UK) supplemented with 5% defibrinated sheep blood (VWR, Radnor, PA) and DENT selective medium (Oxoid). .. Other stimuli used were |